Medical research

Biologists find a way to boost intestinal stem cell populations

Cells that line the intestinal tract are replaced every few days, a high rate of turnover that relies on a healthy population of intestinal stem cells. MIT and University of Tokyo biologists have now found that aging takes ...

Cancer

How the immune system protects us against bowel cancer

Researchers at Universitätsmedizin Berlin have discovered a protective mechanism which is used by the body to protect intestinal stem cells from turning cancerous. The body's innate immune system was found to play a pivotal ...

Diseases, Conditions, Syndromes

Going viral: New cells for norovirus production in the lab

An Osaka University-led research team has developed a system for simply and efficiently producing human norovirus. By coaxing human induced pluripotent stem cells (iPSCs) to develop into a type of cell that usually lines ...

Cancer

Colorectal cancer: Tipping the scales

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its ...

Cancer

Cellular pumps protect the gut from toxins

The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...

Medical research

Stem-cell niche for 10 billion colon cells a day

Researchers at the University of Zurich have discovered the identity of the stem-cell niche of the colon. The niche comprises special cells that activate the stem cells of the adjacent intestinal epithelium and are responsible ...

Medical research

Fasting boosts stem cells' regenerative capacity

As people age, their intestinal stem cells begin to lose their ability to regenerate. These stem cells are the source for all new intestinal cells, so this decline can make it more difficult to recover from gastrointestinal ...

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