MIT biologists have discovered an unexpected effect of a ketogenic, or fat-rich, diet: They showed that high levels of ketone bodies, molecules produced by the breakdown of fat, help the intestine to maintain a large pool ...
Aug 22, 2019
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107
Stem cells can differentiate to replace dead and damaged cells. But how do stem cells decide which type of cell to become in a given situation? Using intestinal organoids, the group of Bon-Kyoung Koo at IMBA and the Institute ...
Nov 24, 2023
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51
Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by ...
Oct 23, 2023
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86
In many ways, our intestines serve as the front gate between our bodies and the world around us. They help digest our food and absorb our medications. They send alarm signals when harmful bacteria, viruses, and allergens ...
Feb 6, 2023
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29
Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids—miniature versions of the small intestine. This will help them to better study the functioning of the small ...
Aug 23, 2022
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22
Investigators at Cedars-Sinai and the University of California, San Francisco (UCSF) have identified a component in the intestine that plays a critical role in repairing damaged tissue.
Aug 4, 2022
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500
As the idea of growing tiny human organs in lab dishes has moved in recent years from futuristic science fiction to actual bioscientific reality, the usefulness of organoids as a research tool for studying the digestive system ...
Jul 28, 2022
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34
A special layer of cells that coats the insides of the small and large intestines takes in nutrients and water while keeping anything bad from circulating. This layer is called the intestinal epithelium. It completely renews ...
Jul 13, 2022
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128
Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea. Such pathogens pose significant ...
Apr 8, 2022
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64
Investigators at the Brigham and the Broad Institute have created specialized, tissue-like structures in the laboratory to model barrier tissues, such as the intestines, to identify new targets for treatment. Barrier tissues ...
Mar 22, 2022
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