Diseases, Conditions, Syndromes

Pathogens use force to breach immune defenses, study finds

Similar to a burglar breaking a window to get into a house, Indiana University researchers have discovered a previously unknown process by which pathogens enter a cell with physical force, breaching the body's immune defenses ...

Immunology

A framework for characterizing dendritic cells

Immunological sentinels known as dendritic cells (DCs) help the body eliminate a wide variety of potential threats, from pathogens to cancer—but they are not all created equal. Some DCs are better at fighting bacteria, ...

Medical research

How tumor necrosis factor protects against infection

Tumour necrosis factor (TNF), a messenger substance in the immune system, plays an important role in triggering chronic inflammatory diseases. For this reason, TNF inhibitors are a standard form of treatment for patients ...

Medications

Do it like the immune system: novel antimicrobials

Microbial infections are becoming unbeatable due to progressive mutations that lead to antimicrobial drug resistance. European scientists exploited the characteristics of novel antimicrobial compounds that mimic the dual ...