Medical research

How type 1 diabetes gradually destroys insulin production

Using the new Imaging Mass Cytometry method, researchers of UZH have investigated the pancreas of healthy organ donors and those with type 1 diabetes. The study shows that many beta cells, which normally produce insulin, ...

Medical research

Next step toward replacement therapy in type 1 diabetes

Scientists have discovered the signals that determine the fate of immature cells in the pancreas. The research shows that they are very mobile and that their destiny is strongly influenced by their immediate environment. ...

Medical research

Uncovering the whole story in diabetes

More than 400 million people worldwide suffer from type 2 diabetes, a disease characterised by increased blood glucose levels, because the body's normal way of controlling insulin release breaks down.

Medical research

Implantable islet cells come with their own oxygen supply

Since the 1960s, researchers have been interested in the possibility of treating type 1 diabetes by transplanting islet cells—the pancreatic cells that are responsible for producing insulin when blood glucose concentration ...

Diabetes

Smart egg cartons to transport cells to cure diabetes

We have developed "smart egg carton" packages for transporting live human pancreas cells for transplantation to diabetic patients. The egg cartons provide oxygen and allow physical separation to prevent damage and death to ...

Immunology

Bystander T cells can steal the show in resolving inflammation

In Type 1 diabetes the immune system mistakenly attacks and destroys insulin-producing pancreatic cells, leaving patients dependent on lifelong insulin injections. The putative perpetrators of the attack—which are called ...

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