Some infants are born with too few nephrons, the filtering units in kidneys that help the body remove waste and excess fluid. Whether due to low birth weight, maternal diabetes, inadequate nutrition or genetic mutations, ...
Mar 15, 2024
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Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings, detailed in a paper published in Science, could lead to the development ...
Feb 22, 2024
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The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers. The study, which uncovered 16 new locations in the genome linked to immunoglobulin A (IgA) ...
Jun 23, 2023
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Diabetes, which affects millions of people worldwide, develops when the body either generates insufficient amounts of the hormone insulin– a hormone that maintains healthy blood sugar—or when the body cannot effectively ...
Nov 2, 2022
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Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults. The finding has implications ...
Oct 12, 2022
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To a certain extent, kidneys have the capacity to repair themselves after being injured, but a switch can occur from such intrinsic repair to incomplete repair that leads to irreversible damage and chronic kidney disease ...
Apr 11, 2022
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Despite impacting an estimated 850 million people and being responsible for 1 in 60 deaths worldwide, few treatments are available for chronic kidney disease. Understanding the genetic variations associated with the disease ...
Aug 13, 2021
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Kidney development is a balancing act between the self-renewal of stem and progenitor cells to maintain and expand their numbers, and the differentiation of these cells into more specialized cell types. In a new study in ...
Apr 1, 2021
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Scientists have successfully produced human kidney tissue within a living organism which is able to produce urine, a first for medical science.
Feb 9, 2018
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The best laid plans of mice and men are a bit different—at least when it comes to kidney development. Compared to a mouse, a human has nearly 100 times more nephrons, the functional units of the kidneys. Humans may owe ...
Mar 18, 2016
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