Diseases, Conditions, Syndromes

Still an unmet need: New therapeutic targets in Alport syndrome

Alport syndrome (AS) is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure. Depending on the mutated gene and the pattern of inheritance, there are three types ...

Diseases, Conditions, Syndromes

Scientists report new approach to reduce or prevent renal fibrosis

Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure. Using genetically altered mice, researchers from Duke University investigated ...

Diseases, Conditions, Syndromes

New therapeutic targets for kidney fibrosis emerge

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population—and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis. Just as fibrosis—or ...

Diseases, Conditions, Syndromes

Kidney disease imaging

Obstructive nephropathy—a condition in which the flow of urine is blocked—is a primary source of kidney impairment in infants and children.

Diseases, Conditions, Syndromes

Preventing fibrosis

Researchers at Cardiff University and the Wales Kidney Research Unit have discovered a potential new method for preventing the process that causes scar formation in organs.

Medical research

New AI technology significantly improves human kidney analysis

The ability to quantify the extent of kidney damage and predict the life remaining in the kidney, using an image obtained at the time when a patient visits the hospital for a kidney biopsy, now is possible using a computer ...

Oncology & Cancer

Diagnostic mutations ID'd in chronic kidney disease patients

(HealthDay)—About one-quarter of adults with chronic kidney disease (CKD) of unknown cause or familial nephropathy or hypertension have diagnostic mutations, which can be identified with whole-exome sequencing (WES), according ...

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