Diseases, Conditions, Syndromes

Iron accumulation: A new insight into fibrotic diseases

Fibrosis is associated with various chronic and life-threatening conditions, including pulmonary fibrosis, liver cirrhosis, kidney disease, and cardiovascular diseases, among others. These conditions collectively contribute ...

Medical research

Scientists discover key step to kidney fibrosis

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following ...

Health

What your hands say about your health

Your hands reveal a lot about the state of your health. This is something that has been recognized since at least the time of Hippocrates—the father of modern medicine.

Medical research

Discovery suppresses progression of kidney fibrosis

Webster Santos is determined to find a way to halt kidney fibrosis, a condition caused by persistent inflammation and assault to the kidney. The disorder leads to kidney disease, itself a pathway to kidney failure, also known ...

Diseases, Conditions, Syndromes

Still an unmet need: New therapeutic targets in Alport syndrome

Alport syndrome (AS) is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure. Depending on the mutated gene and the pattern of inheritance, there are three types ...

Diseases, Conditions, Syndromes

Scientists report new approach to reduce or prevent renal fibrosis

Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure. Using genetically altered mice, researchers from Duke University investigated ...

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