Immunology

Exosomal transmission of viral resistance in Hepatitis B

(Medical Xpress)—To move material in bulk, the standard shipping container used by cells, is the vesicle. These approximately 40-micron sized spheres are essentially recyclable grocery bags that can be loaded and adorned ...

Immunology

Revving up immune system may help treat eczema

The aggravating skin condition eczema is most commonly treated by suppressing the immune system, but not all patients get relief. Now, a drug strategy aimed at revving up the immune system and boosting a type of immune cell ...

Oncology & Cancer

Clues to improve cancer immunotherapy revealed

Cancer immunotherapy drugs trigger the body's immune system to attack tumors and have revolutionized the treatment of certain cancers, such as lymphoma, lung cancer and melanoma. Yet, while some patients respond well to the ...

Immunology

Gut immunity more developed before birth than previously thought

Most biology textbooks explain that the fetal immune system is largely undeveloped and that it learns after being exposed to the world at birth. New research from the University of Pittsburgh School of Medicine and UPMC Children's ...

Diseases, Conditions, Syndromes

People's initial immune response to dengue fever analyzed

Researchers have come one step closer to understanding how the immune system responds to acute dengue fever, a disease that has affected hundreds of thousands of people in Southeast Asia this summer alone. In a study published ...

Medications

PET imaging shows if PD-1 cancer immunotherapy is working

PD-1 is a protein on our T cells that normally keeps these immune cells from running amok. A growing number of cancer drugs are designed to inhibit PD-1, enabling patients' T-cells to attack and kill cancerous cells. PD-1 ...

Oncology & Cancer

Genome screen uncovers new targets for cancer immunotherapy

Immunotherapy has revolutionized the treatment of cancer in the last decade, yet many tumors do not respond to these new therapies. A new genome-wide screen of 20,000 human genes in T cells have turned up several new candidates ...

Medical research

Killer cells the key to potentially life‑saving cancer vaccines

"I'll be honest, when I first started working on this I didn't fully accept it." That's Dr. Andrew Makrigiannis, head of the Department of Microbiology & Immunology, discussing his groundbreaking research on natural killer ...

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