The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation. Also, its aberrant expression and activity ...
Oct 31, 2022
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Cancers are the second leading cause of death in the world, after cardiovascular diseases. Their seriousness lies in their diversity—some can be effectively treated with surgery, chemotherapy and radiotherapy, while others ...
Oct 20, 2022
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The human immune system is a thing of wonder. Up until now it had been widely assumed that the ability of killer T cells to destroy tumor cells and pathogens would deteriorate with age. It turns out, however, that the opposite ...
Sep 21, 2022
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The molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "double positive" CD4+-CD8+ T cells have lately been discovered in people in various ...
Sep 20, 2022
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Natural killer (NK) cells have lately become a hot focus of efforts to develop new immunotherapies. Researchers led by Ludwig Harvard's Tony Letai, whose team collaborated closely with the Ludwig Harvard Kai Wucherpfennig ...
Sep 20, 2022
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Over the last decade, immune checkpoint blockers, or ICBs, have revolutionized treatment for various advanced cancers, including melanoma, the most aggressive skin cancer that was considered largely incurable not long ago. ...
Sep 19, 2022
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Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system. The research, published in Cancer Cell in September, could lead to a new therapeutic ...
Sep 12, 2022
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The Novavax COVID-19 vaccine was approved in Germany this February, followed by the U.S. in mid-July. Immunology professor Martina Sester and her team have now studied how Novavax recipients respond to the vaccine. The study ...
Aug 11, 2022
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Viruses that cause respiratory diseases like the flu and COVID-19 can lead to mild to severe symptoms within the first few weeks of infection. These symptoms typically resolve within a few more weeks, sometimes with the help ...
Aug 5, 2022
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In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order ...
Jul 28, 2022
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