Oncology & Cancer

Improving the conversion success rate of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) presents significant challenges due to its high incidence and mortality rates, particularly in China where most patients are diagnosed at intermediate or advanced stages. This limits the applicability ...

Oncology & Cancer

FDA approves augtyro for NTRK-positive advanced solid tumors

The U.S. Food and Drug Administration has approved Augtyro (repotrectinib), a next-generation tyrosine kinase inhibitor (TKI), for the treatment of patients with neurotrophic tyrosine receptor kinase (NTRK)-positive locally ...

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In chemistry and biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, a process referred to as phosphorylation. Kinases are part of the larger family of phosphotransferases. Kinases are not to be confused with phosphorylases, which carry out phosphorolysis, the breaking of a bond using an inorganic phosphate group; or with phosphatases, which remove phosphate groups.

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