As lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the infection. This strategy can be an important red flag that something is wrong; ...
Apr 10, 2024
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AZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recurrent and newly diagnosed glioblastoma (GBM) patients when given in combination with standard-of-care radiotherapy ...
Apr 9, 2024
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Accumulation of pathologic tau protein plays a pivotal role in the neurodegeneration of Alzheimer's disease (AD) and many other tauopathies. Thus, amelioration of pathological tau aggregates in the brain is an important direction ...
Mar 28, 2024
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Lung cancer is the leading cause of cancer-related death worldwide. Improved understanding of driver mutations of non-small cell lung cancer (NSCLC) has led to more biomarker-directed treatment for patients with advanced ...
Mar 27, 2024
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The U.S. Food and Drug Administration has approved Bristol Myers Squibb's Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T-cell therapy for adult patients with relapsed ...
Mar 19, 2024
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Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators. They have conducted the first whole genome sequencing ...
Mar 4, 2024
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Specific combinations of antihypertensives are recommended for patients with Bruton's tyrosine kinase inhibitor (BTKi)-associated hypertension (HTN), according to a study published online Feb. 5 in Blood Advances.
Feb 19, 2024
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Researchers from the University of Missouri School of Medicine have found potential treatments for two different types of common complications following bone marrow transplantation.
Feb 14, 2024
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For some leukemia patients, the only potential chemotherapy option is a drug that also carries a high risk of heart failure. This means that some patients who recover from their cancer will end up dying of heart disease brought ...
Feb 8, 2024
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Combination treatments with two or more blood pressure drugs can significantly reduce blood pressure in patients taking ibrutinib, according to a new study published in Blood Advances.
Feb 5, 2024
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In chemistry and biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, a process referred to as phosphorylation. Kinases are part of the larger family of phosphotransferases. Kinases are not to be confused with phosphorylases, which carry out phosphorolysis, the breaking of a bond using an inorganic phosphate group; or with phosphatases, which remove phosphate groups.
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