Arthritis & Rheumatism

Effect sizes uncertain for meds versus placebo in knee OA

(HealthDay)—For patients with knee osteoarthritis and at least 12 months of follow-up, there is uncertainty around estimates of effect size for the change in pain in association with medications versus placebo, according ...

Arthritis & Rheumatism

Researcher evaluates estrogen as therapy for knee osteoarthritis

More than 30 million Americans suffer from osteoarthritis of the knee, according to the Centers for Disease Control and Prevention. The degenerative joint disease, often caused by wear and tear, is a leading cause of disability ...

Arthritis & Rheumatism

Hormone therapy may be best defense against knee osteoarthritis

There is an ongoing debate regarding the relationship between knee osteoarthritis and hormone therapy (HT), with small-scale studies providing mixed results. A new large-scale study from Korea shows that women receiving HT ...

Arthritis & Rheumatism

Radiographic knee osteoarthritis tied to increased risk for death

(HealthDay)—Radiographic knee osteoarthritis (RKOA) is associated with an increased risk for mortality from cardiovascular disease (CVD), diabetes, and renal diseases, but self-reported OA is not, according to a study published ...

Arthritis & Rheumatism

Finger joint enlargements may be linked to knee osteoarthritis

Heberden's nodes (HNs) are bony enlargements of the finger joints that are readily detectable in a routine physical exam and are considered hallmarks of osteoarthritis. A new Arthritis & Rheumatology study found that the ...

Knee

The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation. Since in humans the knee supports nearly the entire weight of the body, it is the joint most vulnerable both to acute injury and the development of osteoarthritis.

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