Deep reservoirs of 'sleeper' viruses are roadblocks to HIV cure
The major obstacle to curing HIV is a vast reservoir of "latent, replication-competent proviruses," which have infiltrated the very cells that help orchestrate the immune response.
The major obstacle to curing HIV is a vast reservoir of "latent, replication-competent proviruses," which have infiltrated the very cells that help orchestrate the immune response.
An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor. SLFN 12 shuts down ...
May 10, 2023
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Measuring changes in the speed of electrical signals along nerves connecting the eyes to the brain may accurately reflect recovery from myelin loss in multiple sclerosis (MS), according to researchers at the University of ...
Dec 16, 2019
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HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.
Mar 8, 2018
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(Medical Xpress) -- A team of researchers led by the University of North Carolina School of Medicine has demonstrated that latency develops soon after infection and slows when antiretroviral therapy is given.
May 30, 2012
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Exercise appears to be a potentially effective way of treating premature ejaculation, according to a new study carried out by Anglia Ruskin University (ARU).
Mar 7, 2023
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As his title implies, for David Margolis, MD, director of the UNC HIV Cure Center, treating the virus and its symptoms simply isn't enough.
Dec 1, 2016
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A cure for HIV requires the eradication of latent (i.e., dormant and therefore hidden) virus from reservoirs in immune cells throughout the body. HIV latency depends on the activity of proteins from the human host called ...
Sep 17, 2015
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A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion ...
Apr 17, 2012
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The ability for HIV to hide in the body in a dormant state makes curing the 40 million people living with the virus a challenge. Researchers at the University of North Carolina at Chapel Hill have shown the drug Vorinostat ...
Aug 1, 2017
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