Discovered more than two decades ago, the hormone leptin has been widely hailed as the key regulator of leanness. Yet, the pivotal experiments that probe the function of this protein and unravel the precise mechanism of its ...
Jun 23, 2017
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The global obesity epidemic is so far-reaching it now has an overarching name: globesity. Texas Biomed Staff Scientist Raul Bastarrachea, M.D., is part of a team that discovered a new mutation in the gene that regulates the ...
Jun 21, 2019
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Researchers at Georgetown University Medical Center have revealed how a mutation in a single gene is responsible for the inability of neurons to effectively pass along appetite suppressing signals from the body to the right ...
Mar 18, 2012
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Obesity is a major public-health problem in the United States and around the world, with an estimated 650 million people suffering from the condition. One of the biggest challenges of this ever-worsening condition is figuring ...
Mar 6, 2019
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An international team of doctors and medical scientists has found two rare leptin variants in two children. Both variants led to hyperphagia and obesity. In their study, reported in The New England Journal of Medicine, the ...
Researchers at the University of Michigan Life Sciences Institute have identified a hormone produced by the liver that tells the body to downshift its metabolism when it's expending a lot of energy.
Jan 14, 2019
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A new study from Uppsala University demonstrates that elderly humans carrying a common variant of the fat mass and obesity gene FTO also have a shifted endocrine balance. Low blood concentrations of the satiety hormone leptin ...
Jun 11, 2014
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Delivering the hormone leptin directly to the brain through gene therapy aids weight loss without the significant side effect of bone loss, according to new collaborative research from Oregon State University and University ...
Oct 21, 2015
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B12 deficiency during pregnancy may predispose children to metabolic problems such as type-2 diabetes, according to research presented today at the Society for Endocrinology's annual Conference in Brighton. These findings ...
Nov 7, 2016
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For years, scientists have failed to locate the DNA variants that control the weight-regulating hormone, leptin. However, new research has enabled the identification of four genes associated with leptin levels, which is particularly ...
Feb 11, 2016
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