An increased concentration of the hormone leptin in fat cells is believed to be responsible for weight gain associated with antipsychotic drugs, according to research led by UT Southwestern Medical Center. The study, published ...
Jan 9, 2024
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Damage to the body's peripheral nerves can cause pain and movement disorders. Researchers at the Leipzig University have recently investigated how damaged nerves can regenerate better. They found that fat tissue strongly ...
Nov 28, 2023
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Losing weight conveniently, cheaply, safely. That's been the holy grail of weight-loss ever since 19th century English undertaker and weight-loss celebrity William Banting's 1863 Letter on Corpulence promoted his "miraculous" ...
Aug 9, 2023
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An international team of doctors and medical scientists has found two rare leptin variants in two children. Both variants led to hyperphagia and obesity. In their study, reported in The New England Journal of Medicine, the ...
Polycystic ovarian syndrome, or PCOS, can cause a range of symptoms, including disrupted menstrual cycles, abdominal obesity, cardiovascular disease, and type 2 diabetes. It's also one of the biggest causes of infertility—in ...
Apr 18, 2023
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To eat or to mate—that is the question (and the answer is: moderately hungry mice choose to mate). Researchers publishing in the journal Cell Metabolism on Thursday, February 23, show that hungry mice prioritize interacting ...
Feb 23, 2023
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For many people, keeping a healthy body weight can be a challenge. According to the Centers for Disease Control and Prevention, among adults 20 years old and over, the prevalence of obesity is 42% in the U.S. Obesity-related ...
Jan 3, 2023
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What drives tumor growth? Is it a few rogue cells imposing their will upon healthy tissue, or diseased tissue bringing out the worst in otherwise peaceable cells? Or is it a back-and-forth, a dialogue between the two? According ...
Nov 30, 2022
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A group at MedUni Vienna has identified a regulatory loop controlled by leptin, by which this adipocyte-derived hormone regulates hepatic lipid metabolism via the autonomic nervous system. The study, published in Cell Metabolism, ...
Oct 11, 2022
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A research group at Nagoya University in Japan has discovered a new treatment for type 1 diabetes that uses leptin, a hormone secreted by fat cells. Treating mice models of insulin-dependent diabetes mellitus (a condition ...
Sep 14, 2022
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Leptin (Greek leptos meaning thin) is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The Ob(Lep) gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.
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