Diseases, Conditions, Syndromes

Cattle may spread leptospirosis in Africa, study suggests

University of Otago researchers are helping lead international studies which have discovered that exposure to cattle and rice farming are risk factors for the devastating disease leptospirosis in northern Tanzania.

Diseases, Conditions, Syndromes

Global burden of leptospirosis is greater than thought, and growing

The global burden of a tropical disease known as leptospirosis is far greater than previously estimated, resulting in more than 1 million new infections and nearly 59,000 deaths annually, a new international study led by ...

Diseases, Conditions, Syndromes

Leptospirosis in New York City—a risk from rats to dogs and people

In New York City, leptospirosis, a bacterial disease that affects humans and animals, is most often spread to both people and dogs from rats, according to a study presented at the 2015 International Conference on Emerging ...

Diseases, Conditions, Syndromes

Leptospirosis video potential lifesaver for farmers

A new video series produced and developed by Massey University researchers may save some of the 100 people each year that are affected by leptospirosis.

Diseases, Conditions, Syndromes

Philippine city offers bounties for dead rats

A Philippine city is offering bounties for dead rats in an effort to prevent a repeat of a deadly epidemic spread by rodent urine, an official said Wednesday.

Diseases, Conditions, Syndromes

Six dead in Philippine epidemic caused by rat urine

A bacterial epidemic caused by water contaminated with rat urine has hit a flood-ravaged region in the northern Philippines, killing six people and overwhelming local hospitals, a health official said Wednesday.

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Leptospirosis

Leptospirosis (also known as Weil's syndrome, canicola fever, canefield fever, nanukayami fever, 7-day fever, Rat Catcher's Yellows, Fort Bragg fever, black jaundice and Pretibial fever:290) is caused by infection with bacteria of the genus Leptospira, and affects humans as well as other mammals, birds, amphibians, and reptiles.

The disease was first described by Adolf Weil in 1886 when he reported an "acute infectious disease with enlargement of spleen, jaundice and nephritis". Leptospira was first observed in 1907 from a post mortem renal tissue slice. In 1908, Inada and Ito first identified it as the causative organism and in 1916 noted its presence in rats.

Though recognised among the world's most common diseases transmitted to people from animals, leptospirosis is nonetheless a relatively rare bacterial infection in humans. The infection is commonly transmitted to humans by allowing water that has been contaminated by animal urine to come in contact with unhealed breaks in the skin, the eyes, or with the mucous membranes. Outside of tropical areas, leptospirosis cases have a relatively distinct seasonality with most of them occurring in spring and autumn.[citation needed]

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