Medications

How gut bacteria affect the treatment of Parkinson's disease

Patients with Parkinson's disease are treated with levodopa, which is converted into dopamine, a neurotransmitter in the brain. In a study published on 18 January in the journal Nature Communications, scientists from the ...

Parkinson's & Movement disorders

Gut bacteria could be responsible for side effect of Parkinson's drug

Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson's disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility. ...

Medications

Chinese medicine could treat Parkinson's: HK study

Chinese medicine may be effective in battling certain symptoms of Parkinson's disease, and lessening side effects from the drugs used to treat the condition, according to a new study.

Neuroscience

Gel reduced daily tremors in Parkinson's disease

(Medical Xpress)—An experimental treatment for Parkinson's disease reduced by nearly two hours on average the period each day when medication failed to control patients' slowness and shaking, according to results from a ...

Alzheimer's disease & dementia

Drug may help those with dementia with Lewy bodies

New help may be on the way for people with dementia with Lewy bodies, which is the second most common neurodegenerative type of dementia after Alzheimer's disease. The disease can cause movement problems and issues such as ...

Neuroscience

Investigational drug may reduce involuntary movements

Results of the first randomized, placebo-controlled long-term clinical trial show the investigational drug safinamide may reduce dyskinesia or involuntary movements in mid-to-late stage Parkinson's disease. The findings will ...

Neuroscience

Parkinsons' drug helps older people to make decisions

A drug widely used to treat Parkinson's Disease can help to reverse age-related impairments in decision making in some older people, a study from researchers at the Wellcome Trust Centre for Neuroimaging has shown.

Ophthalmology

Levodopa shows promise against macular degeneration

(HealthDay)— Levodopa (L-dopa) might hold potential for preventing or treating macular degeneration, according to a study published online Oct. 30 in The American Journal of Medicine.

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L-DOPA

L-DOPA (L-3,4-dihydroxyphenylalanine) is a chemical that is made and used as part of the normal biology of some animals and plants. Some animals including humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines. L-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc.). As a drug it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.

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