Medical research

Cinnamon turns up the heat on fat cells

New research from the University of Michigan Life Sciences Institute has determined how a common holiday spice—cinnamon—might be enlisted in the fight against obesity.

Medical research

Our muscles measure the time of day

Biological clocks throughout the body trigger the release of the hormone melatonin during sleep, induce the secretion of digestive enzymes at lunchtime or keep us awake at the busiest moments of the day. A "master clock" ...

Genetics

Epigenetic factors linked to obesity-related disease

Obesity has been linked to "letter" changes at many different sites in the genome, yet these differences do not fully explain the variation in people's body mass index (BMI) or why some overweight people develop health complications ...

Oncology & Cancer

Lipid metabolism is potential 'Achilles' heel' for cancer stem cells

Researchers have discovered a metabolic signature critical for the functioning of "cancer stem cells" that initiate tumor formation. The team also showed how to interfere with this metabolic mechanism in ovarian cancer, inhibiting ...

Medical research

Lung tumors hijack metabolic processes in the liver, study finds

University of California, Irvine scientists who study how circadian rhythms—our own body clocks—control liver function have discovered that cancerous lung tumors can hijack this process and profoundly alter metabolism.

Oncology & Cancer

Research points to a new treatment for pancreatic cancer

Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis, pointing to a potential new treatment using drugs previously developed for atherosclerosis.

Medical research

How a mutated gene wreaks havoc on white matter

An inherited disease of myelin marked by slow, progressive neurological impairment is caused by mutations of a gene that controls lipid metabolism, a finding that may shed insight into mechanisms to control the course of ...

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