A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.
Aug 13, 2021
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In contrast to most antidepressant medications, which can take several weeks to reduce depressive symptoms, ketamine—a commonly used veterinary anesthetic—can lift a person out of a deep depression within minutes of its ...
Jun 21, 2018
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The molecular structure of a protein involved in Alzheimer's disease – and the surprising discovery that it binds cholesterol – could lead to new therapeutics for the disease, Vanderbilt University investigators ...
May 31, 2012
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The human protein apolipoprotein A-I binding protein (AIBP) inhibits HIV replication by targeting lipid rafts and reducing virus-cell fusion, according to a new study published in the premier American Society for Microbiology ...
Feb 10, 2020
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A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...
May 29, 2013
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Researchers have long been intrigued by the antidepressant qualities of the club drug ketamine. Known on the street as "Special K," the drug is taken by partiers for its brief dissociative hallucinogenic effect, but it is ...
May 18, 2017
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Vanderbilt faculty and researchers are looking for the "Achilles' heel" of the cancer cells that survive initial chemotherapy. Michael King, chair of the Department of Biomedical Engineering, and Joshua D. Greenlee, graduate ...
Aug 3, 2021
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Poor diet and lifestyle choices set the stage for obesity and diabetes, but the immune system plays a relatively underappreciated role in accelerating this process. Metabolic changes in fat cells stimulate the release of ...
Mar 15, 2013
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A type of lipid that naturally declines in the aging brain impacts – within laboratory models used to study Parkinson's disease – a protein associated with the disease, according to a study co-authored by University of ...
Sep 9, 2014
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Researchers at the University of Illinois Chicago are a step closer to discovering why it is so difficult for people to withdraw from some antidepressant medications.
May 27, 2021
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