Medical research

New study shows a role for cholesterol in pain perception

When you stub your toe or bump your head, you know that rubbing the injury can lessen the ouch. But how? New research from the lab of Scott B. Hansen, Ph.D., shows how physical pressure on cells can reduce pain signals, while ...

Alzheimer's disease & dementia

Brain cholesterol regulates Alzheimer's plaques, study reveals

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

Medical research

Lipid deficiency linked to neuron degeneration

A type of lipid that naturally declines in the aging brain impacts – within laboratory models used to study Parkinson's disease – a protein associated with the disease, according to a study co-authored by University of ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

Alzheimer's disease & dementia

Alzheimer's protein structure offers new treatment directions

The molecular structure of a protein involved in Alzheimer's disease – and the surprising discovery that it binds cholesterol – could lead to new therapeutics for the disease, Vanderbilt University investigators ...

Medical research

Discovery points to new ways to kill aggressive cancer cells

Vanderbilt faculty and researchers are looking for the "Achilles' heel" of the cancer cells that survive initial chemotherapy. Michael King, chair of the Department of Biomedical Engineering, and Joshua D. Greenlee, graduate ...

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