Medications

Ultrasound-triggered liposomes for on-demand, local anesthesia

Researchers at Boston Children's Hospital have found a new way to non-invasively relieve pain at local sites in the body; such systems could one day improve pain management by replacing addictive opioids and short-lasting ...

Neuroscience

Non-invasive method to deliver drugs to the brain

In a new study researchers from the School of Biomedical Engineering & Imaging Sciences, in collaboration with the Noninvasive Surgery & Biopsy Laboratory led by Dr. James Choi at Imperial College London, have found that ...

Oncology & Cancer

Heat-activated 'grenade' to target cancer

Researchers have developed cancer drug-packed 'grenades' armed with heat sensitive triggers, allowing for treatment to be targeted directly at tumours, according to two studies due to be presented at the National Cancer Research ...

Diseases, Conditions, Syndromes

Mask with myoinositol / trehalose aids adult female acne

(HealthDay)—A ready-to-use peel-off facial mask containing myoinositol and trehalose-loaded liposomes results in clinically detectable improvements in adult female acne (AFA), according to a study published online March ...

Dentistry

Nanotechnology could redefine oral surgery

A trip to the dentist or orthodontist usually instills a sense of dread in most patients, and that's before the exam even begins. Add to that the fear of oral surgery with a painful recovery, and many people will avoid these ...

Immunology

Study could aid development of new drugs to treat gout

Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout. The study, led by Liang Qiao, MD, and his colleagues and collaborators, was published March ...

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Liposome

Liposomes are artificially prepared vesicles made of lipid bilayer. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease. Liposomes can be prepared by disrupting biological membranes, for example by sonication.

Liposomes can be composed of naturally derived phospholipids with mixed lipid chains (like egg phosphatidylethanolamine) or other surfactants. Liposomes should not be confused with micelles and reverse micelles composed of monolayers.

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