Chronic viral infections in the liver can lead to organ dysfunction and ultimately to liver tumors in a progression invariably characterized by viruses that proliferate free of immune system restraints.
Error-correcting mechanisms are very important for cells, because with all the cellular activity constantly going on, malfunctions arise all the time. But when it comes to killing cancer cells, it is in the cells' best interest ...
Jan 27, 2023
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The Liver4Life research has developed a perfusion machine that makes it possible to implant a human organ into a patient after a storage period of three days outside a body. The machine mimics the human body as accurately ...
May 31, 2022
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A team of Duke researchers has discovered that cells lining the gut of zebrafish—and probably humans too—have a remarkable defense mechanism when faced with certain kinds of toxins: they hit the eject button.
Aug 5, 2019
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Prometheus, the mythological figure who stole fire from the gods, was punished for this theft by being bound to a rock. Each day, an eagle swept down and fed on his liver, which then grew back to be eaten again the next day.
Jun 2, 2013
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The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.
May 16, 2011
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Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy. Now, a team led by researchers ...
Apr 19, 2024
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Drug-loaded 3D printed films could change cancer treatments forever as world first research from the University of South Australia shows that new films not only kill more than 80% of liver cancer cells but could also significantly ...
Apr 15, 2024
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In a world-first, QIMR Berghofer scientists have discovered the mechanism that causes severe inflammation among millions of people with chronic liver disease.
Apr 12, 2024
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A custom-made anti-tumor vaccine added to standard immunotherapy was twice as likely to shrink liver cancer as when a patient received immunotherapy alone, a new study shows.
Apr 9, 2024
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Liver cancer is a cancer that starts in the liver. For a thorough understanding of liver cancer it is important to know a brief summary of how the liver works and functions. The liver is the largest organ in the body. It is located below the right lung and under the ribcage. The liver is divided into two lobes: the right lobe and left lobe. Protein is obtained by the liver from a set of sources. The portal vein carries nutrient rich blood from the intestines to the liver and the hepatic artery supplies the liver with blood that is rich in oxygen. Multiple types of tumors can develop in the liver because the liver is made up of many various cells. Tumors that are cancerous are termed malignant and tumors that do not contain cancer are termed benign. Liver cancer is characterized by the presence of malignant hepatic tumors -- tumors or growths on or in the liver (medical terms pertaining to the liver often start in hepato- or hepatic from the Greek word for liver, hēpar, stem hēpat-). They may be discovered on medical imaging (even for a different reason than the cancer itself), or may be present in patients as an abdominal mass, abdominal pain, jaundice, or some other liver dysfunction.
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