Medical research

Researchers discover key player in hepatitis A virus infection

How hepatitis A virus (HAV) manages to enter liver cells called hepatocytes and initiate infection had remained a mystery for fifty years until now. University of North Carolina School of Medicine researchers designed experiments ...

Medical research

New model shows how cells that cause liver cancer are created

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common ...

Medical research

Japan newborn gets liver stem cells in world first

Doctors in Japan have successfully transplanted liver cells derived from embryonic stem cells into a newborn baby, in a world first that could provide new treatment options for infants.

Diseases, Conditions, Syndromes

Malaria vaccine: Could this 'ingredient' be the secret to success?

This ingredient is an essential component of the malaria parasite, a protein known as RPL6, which makes the parasite "visible" to a type of immune cells, the T cells, in the liver. The researchers added the protein to their ...

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Hepatocyte

Hepatocytes make up 70-80% of the cytoplasmic mass of the liver. These cells are involved in protein synthesis, protein storage and transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, and detoxification, modification and excretion of exogenous and endogenous substances. The hepatocyte also initiates the formation and secretion of bile.

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