Medical research

Cholesterol levels sustainably lowered using base editing

Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence. By installing such a point mutation in a specific gene, an international research team led by the University ...

Medications

Evinacumab cuts LDL-C level in familial hypercholesterolemia

(HealthDay)—For patients with homozygous familial hypercholesterolemia, evinacumab lowers low-density lipoprotein (LDL) cholesterol levels, according to a study published in the Aug. 20 issue of the New England Journal ...

Cardiology

Evinacumab cuts cholesterol levels by half in patients with HoFH

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first randomized placebo-controlled ...

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