Oncology & Cancer

Genome screen uncovers new targets for cancer immunotherapy

Immunotherapy has revolutionized the treatment of cancer in the last decade, yet many tumors do not respond to these new therapies. A new genome-wide screen of 20,000 human genes in T cells have turned up several new candidates ...

Oncology & Cancer

Super-powered immune cells

The phase 1 clinical trial will test the feasibility and safety of CAR-T cells—genetically modified white blood cells harvested from a patient's own blood with the unique ability to directly attack and kill cancers—to ...

Medical research

Mechanical forces impact immune response in the lungs

When the body is fending off an infection, there are changes in temperature, pH balance, and metabolism. Yale researchers wondered if yet other factors might come into play, and in a recent study, confirmed that mechanical ...

Medical research

In cystic fibrosis, lungs feed deadly bacteria

In cystic fibrosis, Pseudomonas aeruginosa is a much-feared pathogen. The bacterium easily colonizes the lungs of people with cystic fibrosis, leading to chronic infections that are almost impossible to eradicate and are ...

Medical research

Lung cell transplant boosts healing after the flu in mice

Some cases of the flu are so severe they cause lasting injury to the lungs. New research from the University of Pennsylvania now points to a strategy that may one day offer protection against this damage.

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