Oncology & Cancer

Early genome catastrophes can cause non-smoking lung cancer

Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers. This finding, published in Cell, helps explain how some non-smoking-related ...

Oncology & Cancer

Semaphorin linked to lung cancer treatment resistance

Lung cancer remains a major cause of mortality across the globe, although we are gaining a deeper understanding of the genetic background behind this disease, including the mutations that promote it. Mutation in the gene ...

Oncology & Cancer

Cancer 'signature' first step toward blood test for patients

A discovery by Melbourne researchers could help to identify patients with a particularly aggressive type of lung cancer that are likely to respond to immunotherapies currently used in the clinic to treat other cancers.

Oncology & Cancer

A Braf kinase-inactive mutant induces lung adenocarcinoma

The initiating oncogenic event in almost half of human lung adenocarcinomas is still unknown, complicating the development of selective targeted therapies. Yet these tumours harbour a number of alterations without obvious ...

Oncology & Cancer

New study proves one lung cancer subtype can switch to another

A new study co-authored by a researcher starting her laboratory at the University of Kentucky Markey Cancer Center shows that in certain genetic situations, one non-small cell lung cancer subtype can change into another subtype.

page 1 from 6