Oncology & Cancer

Study tracks genomics of lung tumor behavior

A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors.

Radiology & Imaging

PET/CT plays role in lung adenocarcinoma management

According to an article published ahead-of-print in the February 2020 issue of the American Journal of Roentgenology (AJR), fluorodeoxyglucose PET (FDG PET) can be used to predict the histopathologic subtypes and growth patterns ...

Oncology & Cancer

Early genome catastrophes can cause non-smoking lung cancer

Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers. This finding, published in Cell, helps explain how some non-smoking-related ...

Oncology & Cancer

Semaphorin linked to lung cancer treatment resistance

Lung cancer remains a major cause of mortality across the globe, although we are gaining a deeper understanding of the genetic background behind this disease, including the mutations that promote it. Mutation in the gene ...

Oncology & Cancer

Cancer 'signature' first step toward blood test for patients

A discovery by Melbourne researchers could help to identify patients with a particularly aggressive type of lung cancer that are likely to respond to immunotherapies currently used in the clinic to treat other cancers.

Oncology & Cancer

A Braf kinase-inactive mutant induces lung adenocarcinoma

The initiating oncogenic event in almost half of human lung adenocarcinomas is still unknown, complicating the development of selective targeted therapies. Yet these tumours harbour a number of alterations without obvious ...

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