Medical research

How chromosomes keep their loose ends loose

We take it for granted that our chromosomes won't stick together, yet this kind of cellular disaster would happen constantly were it not for a protein called TRF2. Now, scientists at The Scripps Research Institute (TSRI) ...

Genetics

Unraveling a genetic network linked to autism

Donnelly Centre researchers have uncovered a genetic network linked to autism. The findings, described in the journal Molecular Cell, will facilitate developing new therapies for this common neurological disorder.

Oncology & Cancer

Scientists zoom in to watch DNA code being read

Scientists have unveiled incredible images of how the DNA code is read and interpreted—revealing new detail about one of the fundamental processes of life.

Immunology

Rescue protein gives doomed cells a stay of 'execution'

A research team led by St. Jude Children's Research Hospital immunologists has discovered how a set of proteins delays the "executioner" machinery that kills damaged or infected cells in a process called necroptosis. The ...

Oncology & Cancer

Change in a single DNA base drives a childhood cancer

Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form.

Diseases, Conditions, Syndromes

Lab-dish advance against MERS virus

Chinese scientists said Tuesday they had identified a compound that, in lab dish experiments, blocks infection by the deadly Middle East Respiratory Syndrome (MERS) virus.

Neuroscience

DNA damage may cause amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS)—also known as Lou Gehrig's disease—is a neurodegenerative disease that destroys the neurons that control muscle movement. There is no cure for ALS, which kills most patients within ...

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