University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a new and evolutionarily conserved pathway responsible for "closing down" gene activity in the mammalian cell. The finding is ...
Nov 2, 2020
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Mammalian cells seem to be able to memorize anti-viral stimulation at the level of DNA-packaging molecules, enabling faster and greater activation of anti-viral genes in subsequent stimulations, according to a study conducted ...
Oct 25, 2018
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Scientists studying how mammals detect microbes have discovered new components in a crucial pathway that allows immune cells to detect viral invaders. Their research not only deepens the understanding of antiviral responses, ...
Dec 22, 2011
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Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...
Apr 17, 2013
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A Canadian research team has uncovered a new mechanism involved in Bourneville tuberous sclerosis (BTS), a genetic disease of childhood. The team hypothesizes that a mutation in the TSC1 gene causes neurodevelopmental disorders ...
Jun 23, 2021
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An Argonne study has revealed that short-lived mice and longer-living primates develop brain synapses on the exact same timeline, challenging assumptions about disease and aging. What does this mean for humans—and yesterday's ...
Dec 6, 2023
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During fetal development of the mammalian brain, the cerebral cortex undergoes a marked expansion in surface area in some species, which is accommodated by folding of the tissue in species with most expanded neuron numbers ...
Apr 26, 2013
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The identification of a gene that helps to restrict the host range of the modified vaccinia virus Ankara (MVA) could lead to the development of new and improved vaccines against diverse infectious agents, according to a study ...
May 30, 2019
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An engineered peptide provides a new prototype for killing an entire category of resistant bacteria by shredding and dissolving their double-layered membranes, which are thought to protect those microbes from antibiotics.
Jan 24, 2013
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Hypoxia—where a tissue is deprived of an adequate supply of oxygen—is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Study of how cells adapt to this critical stressor, ...
Feb 3, 2021
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