Every cell in our bodies runs on a 24-hour clock, tuned to the night-day, light-dark cycles that have ruled us since the dawn of humanity. The brain acts as timekeeper, keeping the cellular clock in sync with the outside ...
May 13, 2013
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Fat cells store excess energy and signal these levels to the brain. In a new study this week in Nature Medicine, Georgios Paschos PhD, a research associate in the lab of Garret FitzGerald, MD, FRS director of the Institute ...
Nov 11, 2012
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Cells, like ordinary households, produce "garbage" – debris and dysfunctional elements – that need disposal. When the mechanism for taking out this garbage fails, rare genetic diseases called lysosomal storage disorders ...
May 26, 2011
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Cancer research has long focused on targeting the genetic mutations that drive tumors. Many of these genetic changes affect genes that allow mutated cells to replicate out of control. While developing drugs to target these ...
Oct 16, 2023
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Researchers have developed a new type of neural implant that could restore limb function to amputees and others who have lost the use of their arms or legs.
Mar 22, 2023
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Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, ...
Jan 11, 2021
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Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug ...
Jun 18, 2018
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2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.
Mar 13, 2018
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Biological clocks throughout the body trigger the release of the hormone melatonin during sleep, induce the secretion of digestive enzymes at lunchtime or keep us awake at the busiest moments of the day. A "master clock" ...
Oct 2, 2017
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Every day, 17 million HIV-infected people around the world swallow pills that keep the virus inside them at bay.
Jul 31, 2017
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