Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled—a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease. It is ...
Apr 13, 2023
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Statins are the most commonly used medication in lowering blood cholesterol, prescribed to tens of millions in the Western world. Statins act through inhibition of the enzyme HMG CoA reductase. Nearly 20% of statin users ...
Mar 21, 2023
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Researchers have analyzed image and genomic data from the UK Biobank to find insights into rare diseases of the human eye. These include retinal dystrophies—a group of inherited disorders affecting the retina—which are ...
Mar 9, 2023
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Researchers from the UCL Cancer Institute have provided important molecular understanding of how injury may contribute to the development of a relatively rare but often aggressive form of brain tumor called a glioma.
Feb 24, 2023
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In the U.K., disparities in mortality risk factors exist between ethnic groups, with differences in overall mortality, top causes of mortality and individual mortality risk factors, according to a new study published this ...
Feb 23, 2023
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Research led by scientists at St George's, University of London, has discovered 119 areas in the genome that help to determine the size and shape of blood vessels at the back of the eye, and that an increase in "twisting" ...
Feb 10, 2023
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An international study 13 years in the making demonstrates for the first time that degradation in the way DNA is organized and regulated—known as epigenetics—can drive aging in an organism, independently of changes to ...
Jan 12, 2023
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Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are extremely difficult to detect because they exist in a tiny percentage ...
Jan 3, 2023
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Researchers at Lund University in Sweden have identified one of the reasons why the childhood cancer neuroblastoma becomes resistant to chemotherapy. The findings are significant for how future treatments should be designed. ...
Nov 11, 2022
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Scientists have discovered the cause of a rare condition within a part of the genome that has been largely unexplored in medical genetics. A team at the University of Exeter has found genetic changes in a region that controls ...
Nov 7, 2022
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