Oncology & Cancer

Targeted treatment shrinks deadly pediatric brain tumors

Chemotherapy and radiation are effective cancer treatments because they kill rapidly dividing cells, including tumor cells. But for children—whose tiny bodies are still growing—these treatments can cause lifelong damage. ...

Oncology & Cancer

Breakthrough in childhood brain cancer

Scientists led by Newcastle University have been able to identify the group of children needing more intensive, aggressive chemotherapy treatment for the most common form of brain cancer.

Oncology & Cancer

Old drug, new hope for pediatric brain cancer

Some drugs for heart disease might also work against brain cancer, according to an analysis by researchers from the Jackson Laboratory (JAX), Connecticut Children's Medical Center (CCMC), and UConn Health. The researchers ...

Oncology & Cancer

Study holds promise for new pediatric brain tumor treatment

New research published in Nature Communications from scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration with the Stanford University School of Medicine, shows a specific protein ...

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Medulloblastoma

Medulloblastoma is a highly malignant primary brain tumor that originates in the cerebellum or posterior fossa.

Previously, medulloblastomas were thought to represent a subset of primitive neuroectodermal tumor (PNET) of the posterior fossa. However, gene expression profiling has shown that medulloblastomas have a distinct molecular profile and are distinct from other PNET tumors.

Tumors that originate in the cerebellum are referred to as infratentorial because they occur below the tentorium, a thick membrane that separates the cerebral hemispheres of the brain from the cerebellum. Another term for medulloblastoma is infratentorial PNET. Medulloblastoma is the most common PNET originating in the brain.

All PNET tumors of the brain are invasive and rapidly growing tumors that, unlike most brain tumors, spread through the cerebrospinal fluid (CSF) and frequently metastasize to different locations in the brain and spine.

This text uses material from Wikipedia, licensed under CC BY-SA