A protein that has been widely studied owing to its association with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) is also linked to medulloblastoma, a type of central nervous system cancer. Medulloblastoma ...
Feb 7, 2024
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New research is shedding light and potentially expanding options for patients living with medulloblastoma, an aggressive childhood cancer. The work is published in Molecular Cell.
Jan 8, 2024
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A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three ...
Nov 14, 2023
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Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children. They also showed that the mutations change how cancer cells respond to a cancer drug. These findings could lead ...
Aug 7, 2023
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From neurological problems to hearing loss and infertility, survivors of medulloblastoma, an aggressive form of brain cancer, are left with severe physical and cognitive impairments and have an overall mortality rate 21 times ...
Mar 28, 2023
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Research from Johns Hopkins Kimmel Cancer Center experts revealed a type of RNA, previously considered to be "junk," that may help doctors distinguish and treat a subgroup of patients with medulloblastoma.
Mar 23, 2023
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New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.
Mar 6, 2023
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A new research perspective was published in Oncotarget. The paper is titled "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?"
Feb 27, 2023
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An enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster University-led study.
Nov 10, 2022
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An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with the response to chemotherapy in medulloblastomas, ...
Nov 8, 2022
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Medulloblastoma is a highly malignant primary brain tumor that originates in the cerebellum or posterior fossa.
Previously, medulloblastomas were thought to represent a subset of primitive neuroectodermal tumor (PNET) of the posterior fossa. However, gene expression profiling has shown that medulloblastomas have a distinct molecular profile and are distinct from other PNET tumors.
Tumors that originate in the cerebellum are referred to as infratentorial because they occur below the tentorium, a thick membrane that separates the cerebral hemispheres of the brain from the cerebellum. Another term for medulloblastoma is infratentorial PNET. Medulloblastoma is the most common PNET originating in the brain.
All PNET tumors of the brain are invasive and rapidly growing tumors that, unlike most brain tumors, spread through the cerebrospinal fluid (CSF) and frequently metastasize to different locations in the brain and spine.
This text uses material from Wikipedia, licensed under CC BY-SA
