By introducing cancer-causing mutations into healthy skin cells step-by-step, Broad scientists have created models of skin cancer that can reveal the effects of mutations.
Apr 29, 2022
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Mutation of a gene called ARID2 plays a role in increasing the chance that melanoma, a deadly skin cancer, will turn dangerously metastatic, Mount Sinai researchers report.
Apr 18, 2022
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Many melanoma patients are treated with drugs called BRAF or MEK inhibitors that specifically target the mutant proteins created in cancerous tumors. These inhibitors can block the tumors' ability to grow and spread.
Feb 28, 2022
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Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering ...
Feb 28, 2022
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A diet rich in fiber may help some people being treated for melanoma respond to immunotherapy treatment by influencing the gut microbiome, according to a new study led by researchers at the Center for Cancer Research at the ...
Dec 23, 2021
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Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer. Chief among cancer immunotherapies is a treatment known as CAR-T, or chimeric antigen receptor ...
Oct 4, 2021
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In the progressing field of immunotherapy, surprisingly little is known about immunity to metastatic tumors in locations such as lymph nodes, a frequent place where cancers first spread. Not only do lymph nodes act as a gateway ...
Sep 14, 2021
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Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have generated the first "atlas" of human melanocytes located throughout the body. In analyzing the atlas data further, the researchers discovered ...
Sep 3, 2021
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The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight—not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today ...
Jul 30, 2021
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An immunotherapy based on supercharging the immune system's natural killer cells has been effective in treating patients with recurrent leukemia and other difficult to treat blood cancers. Now, researchers at Washington University ...
Jun 29, 2021
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