Oncology & Cancer

Antibiotics may help to treat melanoma

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumors in mice. Their findings were published ...

Oncology & Cancer

Melanoma of the eye: Preclinical tests show path toward treatment

Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new ...

Oncology & Cancer

A new approach to metastatic melanoma discovered

Combining chemotherapy and BRAF oncogene inhibitors is an effective strategy for fighting metastatic melanoma, the leading cause of death from skin cancer in the world. This has been demonstrated in a study by researchers ...

Diseases, Conditions, Syndromes

Q and A: Bleeding moles and skin checks

DEAR MAYO CLINIC: I have a significant number of moles. While most do not bother me, I have at least one that bleeds from time to time. Should I see my doctor for a mole that bleeds?

Oncology & Cancer

Melanoma registry results shine light on rare pediatric cancer

Pediatric melanoma is a rare disease with only around 400 cases diagnosed in the United States every year. To better understand this disease and how best to treat it, St. Jude Children's Research Hospital scientists created ...

Oncology & Cancer

Physical activity does not increase the risk of melanoma

It is safe to be physically active outdoors without having to worry about the risk of melanoma, as long as you follow the sun safety advice, say the researchers behind a large Norwegian study.

Oncology & Cancer

Cell-based immunotherapy shows promise against melanoma

An immunotherapy based on supercharging the immune system's natural killer cells has been effective in treating patients with recurrent leukemia and other difficult to treat blood cancers. Now, researchers at Washington University ...

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Melanoma

Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

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