Alzheimer's disease & dementia

Alzheimer's drug may help treat traumatic brain injury

Traumatic brain injury (TBI) is a major cause of disability and death globally, but medications have generally failed to benefit patients. A new study found that memantine, a drug that is used to treat dementia associated ...

Psychology & Psychiatry

Study finds Alzheimer's drug may reduce the urge to binge eat

The Alzheimer's drug memantine may perform double-duty helping binge eaters control their compulsion. Researchers have demonstrated that memantine, a neuroprotective drug, may reduce the addictive and impulsive behavior associated ...

Alzheimer's disease & dementia

Commonly used dementia drugs can help more patients with Alzheimer's

The dementia drug donepezil (Aricept), already widely used to treat mild to moderate Alzheimer's disease, can also help in moderate to severe patients, according to a report funded by the UK Medical Research Council (MRC) ...

Psychology & Psychiatry

Memantine drug shown to improve memory in those with Down syndrome

Researchers at the University of Colorado School of Medicine have found a drug that boosts memory function in those with Down syndrome, a major milestone in the treatment of this genetic disorder that could significantly ...

Alzheimer's disease & dementia

Alzheimer's drug fails to reduce significant agitation

A drug prescribed for Alzheimer's disease does not ease clinically significant agitation in patients, according to a new study conducted by researchers from the U.K., U.S. and Norway. This is the first randomized controlled ...

Alzheimer's disease & dementia

Aricept helps moderate to severe Alzheimer's too

Alzheimer's disease patients who are taking a commonly prescribed drug can still benefit from it after they progress to moderate-to-severe illness, when it can be tough to tell whether it's doing any good, a new study says.

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Memantine

Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA glutamate receptors. It was first synthesized by Eli Lilly and Company in 1968. Memantine is marketed under the brands Axura and Akatinol by Merz, Namenda by Forest, Ebixa and Abixa by Lundbeck and Memox by Unipharm. Despite years of research, whether memantine has any effect in mild to moderate Alzheimer's disease is unknown.

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