Medical research

Palmitoylation, a new target for anti-cancer drugs

Peripheral membrane proteins temporarily bind to cell membranes, a necessary step for them to be able to fulfill their biological function. To do this, certain enzymes that catalyze their lipid modification come into action. ...

Medications

Nasal antiviral blocks SARS-CoV-2 infection in mice

SARS-CoV-2, the virus that causes COVID-19, has continuously mutated since it emerged in late 2019. This rapid evolution poses challenges for vaccines and treatments designed to target the virus. A booster shot is now needed ...

Immunology

Cannibal immune cells could offer new treatment path

Melbourne researchers have discovered that an immune cell, thought largely to be focused on fighting infection in newborns and infants, can in fact cannibalize the features of other immune cells, making it a potential new ...

Diseases, Conditions, Syndromes

Starving the bacterium that causes pneumonia

The invitations, decorations, candles and the cake – there's a lot to remember when you organise a birthday party for a five-year-old. One thing we thankfully take for granted in Australia is that our five-year-olds reach ...

Diseases, Conditions, Syndromes

Blood test can track the evolution of coronavirus infection

A blood test that quantifies the protein ACE2, the cellular protein that allows entry of the coronavirus into cells, as well as ACE2 fragments produced as a result of interaction with the virus, could be a simple and effective ...

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Membrane protein

A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. More than half of all proteins interact with membranes.

Biological membranes consist of a phospholipid bilayer and a variety of proteins that accomplish vital biological functions. Structural proteins are attached to microfilaments in the cytoskeleton which ensures stability of the cell. Cell recognition proteins allow cells to identify each other and interact. Such proteins are involved in immune response, for example. Membrane enzymes produce a variety of substances essential for cell function. Membrane receptor proteins serve as connection between the cell's internal and external environments. Finally, transport proteins play an important role in the maintenance of concentrations of ions. These transport proteins come in two forms: carrier proteins and channel proteins. Carrier proteins are involved in using the energy released from ATP being broken down to facilitate active transport and ion exchange. These processes ensure that useful substances are able to enter the cell and that toxic substances are pumped out of the cell.

This text uses material from Wikipedia, licensed under CC BY-SA