Genetics

The gene responsible for cognitive defects in Down syndrome

Learning and memory impairments in a Down syndrome mouse model were reversed by correcting expression of a gene that influences the generation of new neurons in the brain. The finding could pave the way to treat the cognitive ...

Neuroscience

Potential target for diabetes-associated Alzheimer's disease

Researchers have identified a protein that may contribute to the progression of Alzheimer's disease pathology in type-2 diabetes, reports a new study of male mice and human brain tissue. The research, published in JNeurosci, ...

Medical research

Study: Bad diets making for bad memories

A poor diet might be damaging more than your waistline—it might be leading to cognitive decline and poor memory, according to Western-led research released this week.

Alzheimer's disease & dementia

Researchers reverse cognitive impairments in mice with dementia

Reversing memory deficits and impairments in spatial learning is a major goal in the field of dementia research. A lack of knowledge about cellular pathways critical to the development of dementia, however, has stood in the ...

Parkinson's & Movement disorders

Parkinson's disease and binge eating

The results of a new study conducted by Damiano Terenzi, Raffaella Rumiati and Marilena Aiello of SISSA show that "binge eating," which affects some Parkinson's patients, is associated with an impairment of working memory. ...

Neuroscience

Mechanism explains how seizures may lead to memory loss

Although it's been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer's disease, how this happens has been puzzling. In a study published in the journal Nature Medicine, ...

Neuroscience

Breaking memory circuits with marijuana

Paranoia. Munchies. Giggles. Sleepiness. Memory loss. Although the effects of cannabinoids–the active components of marijuana–are familiar to many, their neurobiological substrates are poorly characterized. Perhaps the ...

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