Medical research

3-D bioPen: A hydrogel injection to regenerate cartilage

Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage ...

Arthritis & Rheumatism

3-D bioprinting constructs for cartilage regeneration

Cartilage injury is a common cause of joint dysfunction and existing joint prostheses cannot remodel with host joint tissue. However, it is challenging to develop large-scale biomimetic anisotropic constructs that structurally ...

Medical research

Exercise triggers stem cells in muscle

University of Illinois researchers determined that an adult stem cell present in muscle is responsive to exercise, a discovery that may provide a link between exercise and muscle health. The findings could lead to new therapeutic ...

Cardiology

To repair a damaged heart, three cells are better than one

Cell therapy for cardiac regeneration, while promising, has been hampered by issues with long-term survival of the transplanted cells. Now, a technique that combines three different types of cells in a 3-D cluster could improve ...

Medical research

Researchers succeed in cultivating cartilage from stem cells

Researchers have produced stable joint cartilage from adult stem cells originating from bone marrow. This was made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers ...

Medical research

The art of building bone

Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicates the emerging role of chondrocyte-to-osteoblast ...

Cardiology

Study cautions against statins as general preventive medicine

Statins' success in reducing atherosclerosis-related events has elevated the medications to wonder-drug status, with some researchers advocating for their wider use as a preemptive therapy for cardiovascular disease. Using ...

Medical research

Lab-grown organoids hold promise for patient treatments

Ophir Klein is growing teeth, which is just slightly less odd than what Jeffrey Bush is growing – tissues that make up the face. Jason Pomerantz is growing muscle; Sarah Knox is growing salivary glands; and Edward Hsiao ...

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