Oncology & Cancer

New findings illuminate asbestos-induced mesothelioma

Mesothelioma is a very aggressive type of cancer that primarily affects the thin tissue lining of the chest and the abdomen. It leads to approximately 3,200 deaths per year in the U.S. and is often caused by exposure to asbestos.

Oncology & Cancer

'Drug factory' implants eliminate mesothelioma tumors in mice

Rice University and Baylor College of Medicine researchers have shown they can eradicate advanced-stage mesothelioma tumors in mice in just a few days with a treatment combining Rice's cytokine "drug factory" implants and ...

Oncology & Cancer

Gene x environment interactions may help reduce mesothelioma risk

Researchers have recently discovered that certain enzymes binded to each other may help lessen the risk of developing mesothelioma, a cancer of the lining of the lungs and abdomen. The study from University of Hawaiʻi Cancer ...

Oncology & Cancer

AI used in battle against asbestos-linked cancer

International genomics research led by the University of Leicester has used artificial intelligence (AI) to study an aggressive form of cancer, which could improve patient outcomes.

Health

Team publishes landmark asbestos study

A landmark study from The Australian National University (ANU) into the health impacts of living in a house with loose-fill asbestos insulation has been published in the international journal The Lancet Public Health.

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Mesothelioma

Mesothelioma, more precisely malignant mesothelioma, is a rare form of cancer that develops from the protective lining that covers many of the body's internal organs, the mesothelium. It is usually caused by exposure to asbestos.

Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the pericardium (a sac that surrounds the heart), or the tunica vaginalis (a sac that surrounds the testis).

Most people who develop mesothelioma have worked on jobs where they inhaled asbestos, or they have been exposed to asbestos dust and fiber in other ways. It has also been suggested that washing the clothes of a family member who worked with asbestos can put a person at risk for developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases the risk of other asbestos-induced cancers. Those who have been exposed to asbestos have collected damages for asbestos-related disease, including mesothelioma. Compensation via asbestos funds or lawsuits is an important issue in law practices regarding mesothelioma (see asbestos and the law).

The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung. Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. Research about screening tests for the early detection of mesothelioma is ongoing.

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