Diabetes

New insight into the biology of insulin release

In a new study, Yale researchers challenge a long-held assumption about how insulin-producing cells in the pancreas sense and respond to glucose. Their findings could lead to changes in the way that scientists approach the ...

Medical research

A tale of two proteins: The best and worst of metabolic adaptation

The Developmental Origins of Health and Disease (DOHaD) hypothesis is supported by multiple human epidemiological studies and animal studies. It states that the nutritional environment in early life makes people susceptible ...

Medical research

Researchers discover new pathway for improving metabolic health

Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology. ...

Immunology

Challenging metabolism may help fight disease

New research by Swansea University academics has shown that harnessing metabolism at a cellular level may help to relieve or heal a range of disorders.

Genetics

Mice reveal 38 new genes involved in hearing loss

Multiple new genes involved in hearing loss have been revealed in a large study of mouse mutants by researchers from the Wellcome Sanger Institute and King's College London, and colleagues. The new genes identified reveal ...

Genetics

Pathway contributing to fatty liver disease discovered

Researchers from Karolinska Institutet in Sweden have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

Oncology & Cancer

Starving leukemia cells by targeting amino acids

Cancer cells consume sugar at a higher rate than healthy cells, but they're also hungry for amino acids, the building blocks of proteins and other biomolecules. Researchers at Winship Cancer Institute of Emory University ...

Oncology & Cancer

Cancer cells' plasticity makes them harder to stop

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.

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