For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα. The findings, published recently in Science Advances, could help address the growing threat ...
Feb 3, 2023
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The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Jan 13, 2013
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Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I. It is caused by a deficiency of the key enzyme IDUA needed to break down complex sugars in cells. MPS I eventually ...
Jul 28, 2016
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Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers ...
Mar 10, 2022
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(Medical Xpress)—Weill Cornell Medical College in Qatar (WCMC-Q) scientists have drafted a metabolic map of the human body that shows how human metabolism works as a system, and how it can potentially be modified to treat ...
Jun 17, 2014
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Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio have found evidence that directly links disrupted metabolism (energy production in cells) to a common and often fatal ...
Jul 17, 2015
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The Neurometabolic Diseases research team at IDIBELL and CIBER of Rare Diseases (CIBERER), led by ICREA Professor Aurora Pujol, has reported a novel disease affecting myelin in children, leading to severe incapacity and death ...
Jan 10, 2019
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Robert Linhardt is working to forever change the way some of the most widely used drugs in the world are manufactured. Today, in the journal Science, he and his partner in the research, Jian Liu, have announced an important ...
Oct 27, 2011
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Using a specially designed capsule, researchers can now voyage through the digestive system, collecting new data about digestion and microorganisms. The work by a team including researchers at the University of California, ...
May 10, 2023
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(HealthDay)—Cholesterol-lowering therapy with simvastatin reduces the physiological responses to aerobic exercise training in overweight or obese adults who are at increased risk for metabolic syndrome, according to research ...
Jun 28, 2013
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