Medical research

The circadian clock in heart failure

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition. A research team at Baylor College of Medicine and collaborating ...

Cardiology

Reduction in coenzyme A levels linked to heart failure

Reduced levels of coenzyme A (CoA) worsen heart failure and likely help exacerbate cardiac dysfunction during heart failure, according to a new study. In addition, the findings suggest certain metabolic pathways may be disproportionately ...

Immunology

CRISPR screen identifies new anti-inflammatory drug target

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...

Medical research

Understanding and targeting prostate cancer metabolism

South Australian medical researchers have identified a new way in which prostate cancer cells use glucose to grow and survive, which in turn could be the secret to destroying them.

Medical research

Researchers discover a new pathway to tackle follicular lymphoma

In order to grow beyond control, tumors manipulate cell signals to make it appear as if the cells have the nutrients they need. That is the case in follicular lymphoma, a type of tumor that affects the B lymphocytes of the ...

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