Diabetes

Egg metabolites in blood related to lower risk of type 2 diabetes

Consumption of one egg every day seems to associate with a blood metabolite profile that is related to a lower risk of type 2 diabetes, a new study conducted in the University of Eastern Finland shows. The findings were published ...

Medical research

Facilitating diagnosis with a new type of biosensor

Scientists from the Max Planck Institute and EPFL have developed a new type of biosensor able to precisely quantify metabolites using a single drop of blood. The accuracy and simplicity of the procedure could make it a tool ...

Health

Cheating on your diet? This blood test can tell

By analyzing small molecules called metabolites in a blood sample, a scientist can determine if you're following your prescribed diet or cheating, researchers at the Johns Hopkins Bloomberg School of Public Health report.

Cancer

Researchers suggest new treatment for rare inherited cancers

Studying two rare inherited cancer syndromes, Yale Cancer Center (YCC) scientists have found the cancers are driven by a breakdown in how cells repair their DNA. The discovery, published today in Nature Genetics, suggests ...

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Metabolite

Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.

Examples of primary metabolites produced by industrial microbiology:

The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.

Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.

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