Although past research has indicated that moderate alcohol consumption can lower one's risk of cardiovascular disease (CVD), more recent studies suggest that moderate levels of drinking may be hazardous to heart health. A ...
Nov 27, 2023
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A research team has discovered a microbial metabolite that destroys dopamine-producing neurons. Further experiments showed that Parkinson-like symptoms occur as a result.
Oct 11, 2023
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The complex relationship between physical activity and energy balance—food intake versus energy expenditure—is still a challenge for science, especially in light of the rising worldwide prevalence of overweight and obesity. ...
Sep 26, 2023
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Photobiomodulation during sleep turns the brain into a washing machine, helping to cleanse its tissues of toxic beta-amyloid and increase resistance to the progression of Alzheimer's disease.
Sep 22, 2023
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Cardiovascular diseases (CVD) are chronic diseases that cause a serious social problem, and this situation has been improved through risk assessment of CVD. Metabolic factors are the predominant risk factors for CVD.
Sep 21, 2023
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Metabolites produced by gut bacteria during digestion can be used to trigger an immune response against colorectal cancer cells, according to new University of Alberta research, published in Frontiers in Immunology, that ...
Sep 13, 2023
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Since the concept of "gut-joint" axis was proposed, increasing evidence has shown that the imbalance of gut microbiota may play a key role in the occurrence and development of rheumatoid arthritis (RA).
Jul 17, 2023
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An atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine ...
Jun 29, 2023
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A Cleveland Clinic research team has published an "atlas" of metabolites associated with cardiovascular disease in the European Heart Journal. The novel findings provide key details about the routes and potential branching ...
Jun 22, 2023
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Using a specially designed capsule, researchers can now voyage through the digestive system, collecting new data about digestion and microorganisms. The work by a team including researchers at the University of California, ...
May 10, 2023
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Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
Examples of primary metabolites produced by industrial microbiology:
The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.
Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.
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