Oncology & Cancer

Research explores how melanoma grows and spreads

The first step in treating cancer is understanding how it starts, grows and spreads throughout the body. A relatively new cancer research approach is the study of metabolites, the products of different steps in cancer cell ...

Medical research

Melatonin: finally, a supplement that actually boosts memory

Walk down the supplement aisle in your local drugstore and you'll find fish oil, ginkgo, vitamin E, and ginseng, all touted as memory boosters that can help you avoid cognitive decline. You'll also find melatonin, which is ...

Neuroscience

Study finds 10 metabolites associated with risk of stroke

Metabolites are small molecules found in our body's cells. They come from the food we eat, chemical processes happening within our bodies and microbes. A new analysis of recent studies has found that the levels of 10 metabolites ...

Medical research

Gut microbes: The key to normal sleep

With fall and winter holidays coming up, many will be pondering the relationship between food and sleep. Researchers led by Professor Masashi Yanagisawa at the University of Tsukuba in Japan hope they can focus people on ...

Autism spectrum disorders

Managing the microbiome raises new hope for autism

According to the Centers for Disease Research, 1 in 54 children is diagnosed with autism spectrum disorder (ASD) each year, and the number has been rising. The disease causes perplexing, lifelong developmental disabilities, ...

page 1 from 18

Metabolite

Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.

Examples of primary metabolites produced by industrial microbiology:

The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.

Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.

This text uses material from Wikipedia, licensed under CC BY-SA