Genetics
Novel DNA shift discovery may benefit severe immune conditions
Discovery of a DNA shift in the innate immune memory of cells may aid in the fight against one of humans' most deadly foes—sepsis.
Mar 12, 2024
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News tagged with methyl group
Oncology & Cancer
Researchers reveal mechanism of drug reactivating tumor suppressors
Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...
Feb 21, 2024
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Oncology & Cancer
Epigenetic therapy shows promise for endocrine-resistant breast cancer in mice
Endocrine resistance—a major cause of breast cancer deaths—can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered. The team successfully ...
Jan 9, 2024
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Oncology & Cancer
Researchers clarify role of SMYD3 enzyme in prostate cancer progression
Prostate cancer is the most common cancer in men other than skin cancer, and more than 288,000 new cases are diagnosed every year, according to the American Cancer Society. The disease's fatality rate has decreased by more ...
Dec 21, 2023
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Oncology & Cancer
Unraveling predisposition in bilateral Wilms tumor
Children with bilateral Wilms tumor have a tumor in each of their kidneys—a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease. Scientists at St. Jude Children's Research ...
Dec 18, 2023
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Cardiology
Reprogramming of energy metabolism restores cardiac function after infarction in mice
After birth, the human heart loses its regenerative capacity almost completely. Damage to the heart muscle—for example, due to a heart attack—therefore usually leads to a permanent loss of function in adults. Scientists ...
Oct 24, 2023
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Genetics
DOT1L gene variants associated with a new neurological disorder
A study from the laboratory of Dr. Hugo J. Bellen, a distinguished service professor at Baylor College of Medicine and a principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas ...
Oct 13, 2023
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Genetics
Study illuminates mechanism that annotates genetic information passed from fathers to offspring
Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.
Sep 6, 2023
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Medical research
Stem cell studies tune into hearing regeneration
A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don't regenerate after damage. In two new studies, published in the Proceedings of the National Academy of the Sciences ...
Aug 14, 2023
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Health
Marijuana use linked to epigenetic changes
Recent and long-term marijuana use is linked to changes in the human epigenome, a new Northwestern Medicine study published in Molecular Psychiatry has found.
Jul 20, 2023
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