Compared to newborns conceived traditionally, newborns conceived through in vitro fertilization (IVF) are more likely to have certain chemical modifications to their DNA, according to a study by researchers at the National ...
Apr 14, 2021
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Huntington's disease is a genetic neurodegenerative disorder caused by mutations in the protein huntingtin and characterized by involuntary dance-like movements, severe behavioral changes and cognitive impairment. That neuronal ...
Apr 13, 2021
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Researchers at the National Institutes of Health (NIH) have discovered specific regions within the DNA of neurons that accumulate a certain type of damage (called single-strand breaks or SSBs). This accumulation of SSBs appears ...
Mar 25, 2021
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Disorders of cellular energy supply can cause a number of serious diseases, but also seem to be connected to aging. More research is needed on mitochondrial function to find future treatments. A new study involving researchers ...
Feb 22, 2021
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SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...
Dec 23, 2020
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Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting ...
Oct 26, 2020
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A new study led by UC Davis MIND Institute researchers found a distinct DNA methylation signature in the cord blood of newborns who were eventually diagnosed with autism spectrum disorder (ASD). This signature mark spanned ...
Oct 22, 2020
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A one-two punch of changing gene expression, then deploying immune checkpoint inhibitors, shows promise in battling one of the most treatment-resistant types of cancer in preclinical models, according to a new publication ...
Sep 30, 2020
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A team of researchers affiliated with multiple institutions in Europe has found a connection between patients who show more DNA methylation at some genome sites and a higher likelihood of failing to respond to metformin. ...
The endogenous regulation of a specific gene is associated with a reduced risk of developing post-traumatic stress disorder following a terrifying experience. In particular, traumatic memories of the experience are less severe. ...
Aug 17, 2020
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