Humankind has a longstanding obsession with eternal youth. Stories about elixirs of life and fountains that quench one's thirst for immortality have stirred our imagination since time immemorial. Different versions of these ...
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Phthalates, which are used as plasticizers in plastics, can considerably increase the risk of allergies among children. This was demonstrated by UFZ researchers in conjunction with scientists from the University of Leipzig ...
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Purdue University and Indiana University School of Medicine scientists were able to force an epigenetic reaction that turns on and off a gene known to determine the fate of the neural stem cells, a finding that could lead ...
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The fate of stem cells is determined by series of choices that sequentially narrow their available options until stem cells' offspring have found their station and purpose in the body. Their decisions are guided in part by ...
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To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. Now, new research shows how ...
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The lack of oxygen in tumor cells changes the cells' gene expression, thereby contributing to the growth of cancer. This is the main conclusion of a research project led by professor Diether Lambrechts and Dr. Bernard Thienpont ...
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New research suggests that early severe social deprivation may impact DNA modifications that affect the expression of stress-related genes. These nongenetic (or epigenetic) modifications occur when molecules called methyl ...
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A team of scientists in Japan has found that a DNA modification called 5hmC – thought to be involved in turning genes on and off – localizes at sites of DNA damage and repair. They also found that a family of recently ...
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Stopping disruptions in cellular "trash removal" brought on by errors in molecular marks on DNA may guard against neurodegenerative diseases like Parkinson's.
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Apart from the hereditary information that is encoded in the sequence of bases in DNA, there is a second code of life: Chemical alterations in DNA or in its packaging proteins form an additional regulatory level that determines ...
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