Autism spectrum disorders

Placenta may hold clues for early autism diagnosis and intervention

New UC Davis MIND Institute research has identified a novel human gene linked to fetal brain development and autism spectrum disorder (ASD). The discovery also links the gene to the mother's early prenatal vitamin use and ...

Psychology & Psychiatry

Scientists gain new understanding of how brain cells talk

Experts from the University of Nottingham have discovered that reversing the modification of molecular messages at synapses in the human brain, may contribute to reversible mental health conditions such as anxiety, and memory ...

Oncology & Cancer

Genetic and epigenetic 'origin story' of pediatric liver cancer

Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.

Psychology & Psychiatry

A new way to treat PTSD?

Exposure to a traumatic experience can lead to post-traumatic stress disorder (PTSD), an incapacitating disorder in susceptible persons with no reliable therapy. Particularly puzzling is understanding how transient exposure ...

Neuroscience

How environmental factors could provide for a young brain

A stimulating environment keeps the "hippocampus"—which is the brain's memory control center—young, so to speak. Causes of this are molecular mechanisms that affect gene regulation. These current findings from studies ...

Diseases, Conditions, Syndromes

Huntington's Disease: Neural traffic could help understand the disease

Huntington's disease is a genetic neurodegenerative disorder caused by mutations in the protein huntingtin and characterized by involuntary dance-like movements, severe behavioral changes and cognitive impairment. That neuronal ...

Neuroscience

DNA damage 'hot spots' discovered within neurons

Researchers at the National Institutes of Health (NIH) have discovered specific regions within the DNA of neurons that accumulate a certain type of damage (called single-strand breaks or SSBs). This accumulation of SSBs appears ...

Medical research

Changing the perspective on the 'Cinderella of the cytoskeleton'

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...

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