Neuroscience

Stroke produces dysfunctional brain cells

Mice produce new neurons in the hippocampus following a stroke that fail to develop properly, finds new research published in JNeurosci. Intervening in the production of these cells may help to mitigate stroke-induced memory ...

Cancer

Stopping cancer from recruiting immune system double agents

Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread). A ...

Medical research

Obese mice lose anxiety when 'zombie cells' exit their brain

Mayo Clinic researchers and collaborators have shown in mice that obesity increases the level of "zombie" or senescent cells in the brain, and that those cells, in turn, are linked to anxiety. When senolytic drugs are used ...

Medical research

The immune system's fountain of youth

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future. ...

Cancer

Breast cancer drugs could help treat resistant lung cancers

A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, suggests a new study in mice from the Francis Crick Institute and the Institute of ...

Alzheimer's disease & dementia

Experimental Alzheimer's drug improves memory in mice

An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein ...

Neuroscience

Drugs of abuse: Identifying the addiction circuit

What happens in the brain of a compulsive drug user? What is the difference in brain function between an addict and a person who takes a drug in a controlled manner? In an attempt solve this puzzle, neurobiologists at the ...

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