Combining ultrasound and bubbles helps medicines reach the brain
Luckily, the brain has a filter that protects it and the rest of the central nervous system from foreign elements like pathogens that can damage the tissue.
Aug 2, 2022
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Luckily, the brain has a filter that protects it and the rest of the central nervous system from foreign elements like pathogens that can damage the tissue.
Aug 2, 2022
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MRI-guided focused ultrasound combined with microbubbles can open the blood-brain barrier (BBB) and allow therapeutic drugs to reach the diseased brain location under the guidance of MRI. It is a promising technique that ...
Jul 12, 2021
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An international research team led by Dr. Tali Ilovitsh of the Biomedical Engineering Department at Tel Aviv University developed a noninvasive technology platform for gene delivery into breast cancer cells. The technique ...
Jun 24, 2020
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The blood-brain barrier - the semi-permeable membrane that surrounds the brain - offers important protection for a delicate organ, but in some cases, clinicians need to get past the barrier to deliver vital drugs to treat ...
Nov 15, 2017
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For most of our tissues and cells, a lack of oxygen, or hypoxia, is bad news. Cancer cells, on the other hand, can thrive in these hypoxic conditions, which render tumors less susceptible to anti-cancer treatments, including ...
Jul 10, 2023
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Researchers at the Beckman Institute for Advanced Science and Technology have used deep learning to develop a new framework for super-resolution ultrasound.
May 25, 2023
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Blood carries vital oxygen through our circulation system to muscles and organs. Acoustic tools can create small bubbles in our blood, capable of changing in response to oxygen and signifying oxygen levels.
Nov 29, 2021
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Application of low-intensity pulsed ultrasound in combination with microbubbles might enhance the delivery of chemotherapy medication used for treating cancers. In their study, a team of Lithuanian researchers from three ...
Dec 17, 2020
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A new pilot study from the Icahn School of Medicine at Mount Sinai suggests that COVID-19 is causing significant dilation of the blood vessels of the lung, specifically the capillaries. This vasodilation is contributing to ...
Aug 19, 2020
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An ultrasound imaging technique called passive cavitation imaging was able to create an image and estimate the amount of a drug that crossed the blood-brain barrier to reach a specific location in the brain, according to ...
Jun 18, 2019
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Microbubbles are bubbles smaller than one millimetre in diameter, but larger than one micrometre. They are used in medical diagnostics as a contrast agent for ultrasound imaging. The gas-filled, e.g. air or perfluorocarbon, microbubbles oscillate and vibrate when a sonic energy field is applied and may reflect ultrasound waves. This distinguishes the microbubbles from surrounding tissues. In practice, because gas bubbles in liquid lack stability and would therefore quickly dissolve, microbubbles must be encapsulated with a solid shell. The shell is made from either a lipid or a protein such as Optison microbubbles which consist of perfluoropropane gas encapsulated by a serum albumin shell.
Microbubbles may also be used for drug delivery and water/waste water treatment purposes. .
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