An international team of researchers has developed a way to replace almost all of the microglia cells in a mouse brain using circulation-derived myeloid cells as a way to treat neurodegenerative disease using a technique ...
Researchers at Johns Hopkins Medicine report evidence that zebrafishes' natural ability to regenerate their eyes' retinal tissue can be accelerated by controlling the fishes' immune systems. Because evolution likely conserved ...
Jul 17, 2017
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Mount Sinai researchers have achieved an unprecedented understanding of the genetic and molecular machinery in human microglia—immune cells that reside in the brain—that could provide valuable insights into how they contribute ...
Aug 5, 2022
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Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill ...
Apr 14, 2022
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A newly discovered "energy switch" in the immune cells of the brain may lead to the development of drugs for Alzheimer's disease, the most common form of dementia.
Mar 15, 2023
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Messy tangles of a protein called tau can be found in the brains of people with Alzheimer's disease and some other neurodegenerative diseases. In Alzheimer's, the tangles coalesce just before tissue damage becomes visible ...
Oct 10, 2019
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New research from the University of Virginia School of Medicine is shedding light on the development of the brain's immune defenses—and how those defenses respond to strokes that strike one in 4,000 babies in the first ...
Aug 31, 2020
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(Medical Xpress)—The World health Organization calls depression "the leading cause of disability worldwide," causing more years of disability than cancer, HIV/AIDS, and cardiovascular and respiratory diseases combined. ...
Jan 8, 2014
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Microglia are known to be important to brain function. The immune cells have been found to protect the brain from injury and infection and are critical during brain development, helping circuits wire properly. They also seem ...
Dec 6, 2018
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As scientists search for the roots of Alzheimer's disease, they have had a hard time determining whether microglia, an immune system cell crucial to brain development and maintenance of the adult brain, is a friend or foe.
Feb 4, 2022
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