Autism spectrum disorders

Autism in males linked to defect in brain immune cells, microglia

Many cases of autism spectrum disorders (ASDs) may result from problems in immune cells that normally work to trim back unneeded brain connections in early life, suggests a new study led by scientists at Scripps Research.

Alzheimer's disease & dementia

Pathway discovered that prevents buildup of Alzheimer's protein

St. Jude Children's Research Hospital scientists have discovered a pathway that functions like a car wash to prevent the buildup of a toxic protein associated with Alzheimer's disease. The report appeared online today in ...

Neuroscience

Microglial methylation "landscape" in human brain

In the central nervous system, microglial cells play critical roles in development, aging, brain homeostasis, and pathology. Recent studies have shown variation in the gene-expression profile and phenotype of microglia across ...

Alzheimer's disease & dementia

How does alcohol influence the development of Alzheimer's disease?

Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta—the protein that forms globs of plaques ...

Neuroscience

Immune cells in the brain share the work

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases ...

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